INNOVATIVE APPROACHES IN IMMUNOMODULATION FOR CELL-BASED THERAPIES

Muhammad Zubair Zafar*1, Muhammad Saleem Iqbal2, Babar Rafique Khan3, Aliya Shaima4, Hooria Amir5, Muhammad Maroof6, Rashid Nawaz7, Shehzad Ahmad Sattar8, Waseem Haidar9, Samar Ali Shah8 and Muhammad Rasim10

1Faisalabad Medical University, Allied Hospital Faisalabad, Pakistan 2Department of Surgery, Faisalabad Medical University, Faisalabad, Pakistan 3Department of ENT, Allied Hospital Faisalabad, Pakistan 4Faisalabad Medical University Faisalabad, Pakistan 5Department of Physiology, Faisalabad Medical University, Faisalabad, Pakistan 6Medicine Allied Hospital, Faisalabad, Pakistan 7Department of Pediatrics, Faisalabad Medical University, Faisalabad, Pakistan 8 Department of Surgery, Faisalabad Medical University, Allied Hospital Faisalabad, Pakistan 9Department of Pulmonology, Faisalabad Medical University, Allied Hospital Faisalabad, Pakistan 10Department of Pediatrics, Faisalabad Medical University, Allied Hospital Faisalabad, Pakistan

zafarzubairrana@gmail.com

To Cite this Article :

Zafar MZ, Iqbal MS, Khan BR, Shaima A, Amir H, Maroof M, Nawaz R, Sattar SA, Haidar W, Shah SA and Rasim M, 2025. Innovative approaches in immunomodulation for cell-based therapies. Agrobiological Records 19: 59-70. https://doi.org/10.47278/journal.abr/2025.008

Abstract

The field of medicine is on the verge of transforming with the help of cellular therapies, which can address a wide range of diseases by restoring dysfunctional tissues more dynamically than conventional drugs. These therapies include stem and non-stem cells sourced from different places and apply to diverse therapeutic areas, such as cancer, immune disorders, and regenerative medicine. Cellular therapies have received numerous clinical approvals, and many trials are underway. In these therapies, the recipient immune reaction remains a significant hindrance to favorable results. This review analyzes the latest investigations regarding immune system modulators to reduce immune rejection or enhance immune ability to tolerate cellular therapies. We talk over the capacity of these interventions to accelerate translation for productive results of cellular therapies to succeed in medical settings.


Article Overview

  • Volume : 19
  • Pages : 59-70