Fungi: A Potential Source of Biopharmaceuticals
Umar Farooq Gohar1,*, Hamid Mukhtar1, Amir Mushtaq2, Ayesha Farooq1, Farooq Saleem3, Malik Asif Hussain4
and Muhammad Usman Ghani5
1Institute of Industrial Biotechnology, Government College University, Lahore 54000, Pakistan,
2Ghulab Devi College of Pharmacy, Lahore 54000, Pakistan,
3Faculty of Pharmacy, The university of Lahore, Lahore, Pakistan,
4College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia,
5Pharmacy Department Jinnah Hospital Lahore, Pakistan.
*Corresponding Author: firstname.lastname@example.org
This review is related to important antibacterial, antimycotic, antilipemic, immunosuppressive or immunomodulator and anti-tumor agents that occur naturally in various fungi, including marine fungi, endophytic fungi, soil fungi and environmental fungi. The purpose of this assessment is to show the drugs produced by fungi and the use of these drugs for pharmaceutical purposes. Right after the discovery of the first β-lactam antibiotic, penicillin, fungi have become the source of modern medicine including several important antibiotics to treat potentially deadly infections. With the discovery of new fungi and their fungal metabolites, began a new era in immuno-pharmacology and organ transplantation. The advancements and developments of medicines from natural products not only play a vital role in therapeutic applications of these active secondary metabolites but they also play a role in semi synthetic modifications of natural products to improve their activity and to synthetically develop their structural imitations. So, it is concluded that the fungi are the potential source of the secondary metabolites and biopharmaceuticals.
Keywords: Marine-Derived Fungi, Fungal Metabolites, Natural Products, Anti-Cancer